1xxq
From Proteopedia
(Difference between revisions)
| Line 4: | Line 4: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1xxq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Morus_nigra Morus nigra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XXQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XXQ FirstGlance]. <br> | <table><tr><td colspan='2'>[[1xxq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Morus_nigra Morus nigra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XXQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XXQ FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xxq OCA], [https://pdbe.org/1xxq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xxq RCSB], [https://www.ebi.ac.uk/pdbsum/1xxq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xxq ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xxq OCA], [https://pdbe.org/1xxq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xxq RCSB], [https://www.ebi.ac.uk/pdbsum/1xxq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xxq ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q8LGR3_MORNI Q8LGR3_MORNI] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 18: | Line 20: | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xxq ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xxq ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | The structures of MornigaM and the MornigaM-mannose complex have been determined at 1.8 A and 2.0 A resolution, respectively. Both structures adopt the typical beta-prism motif found in other jacalin-related lectins and their tetrameric assembly closely resembles that of jacalin. The carbohydrate-binding cavity of MornigaM readily binds mannose. No major structural rearrangements can be observed in MornigaM upon binding of mannose. These results allow corroboration of the structure-function relationships within the small group of Moraceae lectins. | ||
| - | |||
| - | Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose.,Rabijns A, Barre A, Van Damme EJ, Peumans WJ, De Ranter CJ, Rouge P FEBS J. 2005 Jul;272(14):3725-32. PMID:16008570<ref>PMID:16008570</ref> | ||
| - | |||
| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 1xxq" style="background-color:#fffaf0;"></div> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Morus nigra]] | [[Category: Morus nigra]] | ||
| - | [[Category: Barre | + | [[Category: Barre A]] |
| - | [[Category: | + | [[Category: De Ranter CJ]] |
| - | [[Category: Peumans | + | [[Category: Peumans WJ]] |
| - | [[Category: Rabijns | + | [[Category: Rabijns A]] |
| - | + | [[Category: Rouge P]] | |
| - | [[Category: Rouge | + | [[Category: Van Damme EJM]] |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
Current revision
Structure of a mannose-specific jacalin-related lectin from Morus nigra
| |||||||||||
