2dzo

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Current revision (13:48, 13 March 2024) (edit) (undo)
 
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<StructureSection load='2dzo' size='340' side='right'caption='[[2dzo]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='2dzo' size='340' side='right'caption='[[2dzo]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dzo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DZO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dzo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DZO FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2dzn|2dzn]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dzo OCA], [https://pdbe.org/2dzo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dzo RCSB], [https://www.ebi.ac.uk/pdbsum/2dzo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dzo ProSAT], [https://www.topsan.org/Proteins/RSGI/2dzo TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dzo OCA], [https://pdbe.org/2dzo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dzo RCSB], [https://www.ebi.ac.uk/pdbsum/2dzo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dzo ProSAT], [https://www.topsan.org/Proteins/RSGI/2dzo TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PSD10_YEAST PSD10_YEAST]] Acts as a chaperone during the assembly of the 26S proteasome, specifically of the 19S regulatory complex (RC) and appears to have an overlapping role with RPN14.<ref>PMID:19412159</ref> <ref>PMID:19446322</ref> <ref>PMID:9714768</ref> [[https://www.uniprot.org/uniprot/PRS6B_YEAST PRS6B_YEAST]] The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).
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[https://www.uniprot.org/uniprot/PSD10_YEAST PSD10_YEAST] Acts as a chaperone during the assembly of the 26S proteasome, specifically of the 19S regulatory complex (RC) and appears to have an overlapping role with RPN14.<ref>PMID:19412159</ref> <ref>PMID:19446322</ref> <ref>PMID:9714768</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 18824]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Nakamura, Y]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Padmanabhan, B]]
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[[Category: Nakamura Y]]
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[[Category: Structural genomic]]
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[[Category: Padmanabhan B]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: A-helical domain]]
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[[Category: Ankyrin repeat]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Protein binding]]
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[[Category: Rsgi]]
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Current revision

Crystal structure analysis of yeast Nas6p complexed with the proteasome subunit, rpt3

PDB ID 2dzo

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