2pl2
From Proteopedia
(Difference between revisions)
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<StructureSection load='2pl2' size='340' side='right'caption='[[2pl2]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='2pl2' size='340' side='right'caption='[[2pl2]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2pl2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2pl2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PL2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PL2 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pl2 OCA], [https://pdbe.org/2pl2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pl2 RCSB], [https://www.ebi.ac.uk/pdbsum/2pl2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pl2 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pl2 OCA], [https://pdbe.org/2pl2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pl2 RCSB], [https://www.ebi.ac.uk/pdbsum/2pl2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pl2 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q72L02_THET2 Q72L02_THET2] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pl2 ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pl2 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | The hypothetical protein TTC0263 of Thermus thermophilus HB27 is a thermophilic tetratricopeptide repeat (TPR)-containing protein. In the present study, the TPR region (residues 26-230) was resolved at 2.5 A with R-factors of R/Rfree = 23.6%/28.6%. TTC0263 consists of 11 helices that form five TPR units. Uniquely, it contains one atypical "extended" TPR (eTPR) unit. This comprises extended helical residues near the loop region of TTC0263, such that the helical length of eTPR is longer than that of the canonical TPR sequence. In addition, the hybrid TPR domain of TTC0263 possesses oligomer-forming characteristics. TPR domains are generally involved in forming multi-subunit complexes by interacting with each other or with other subunit proteins. The dynamic structure of TTC0263 described here goes some way to explaining how TPR domains mediate the formation of multi-subunit complexes. | ||
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| - | Crystal structure of TTC0263, a thermophilic TPR protein from Thermus thermophilus HB27.,Lim H, Kim K, Han D, Oh J, Kim Y Mol Cells. 2007 Aug 31;24(1):27-36. PMID:17846496<ref>PMID:17846496</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 2pl2" style="background-color:#fffaf0;"></div> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Thermus thermophilus HB27]] |
| - | [[Category: Han | + | [[Category: Han D]] |
| - | [[Category: Kim | + | [[Category: Kim K]] |
| - | [[Category: Lim | + | [[Category: Lim H]] |
| - | [[Category: Oh | + | [[Category: Oh J]] |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of TTC0263: a thermophilic TPR protein in Thermus thermophilus HB27
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