2z15

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Current revision (13:55, 13 March 2024) (edit) (undo)
 
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<StructureSection load='2z15' size='340' side='right'caption='[[2z15]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2z15' size='340' side='right'caption='[[2z15]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2z15]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z15 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2z15]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z15 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TOB1, TOB, TROB1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z15 OCA], [https://pdbe.org/2z15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z15 RCSB], [https://www.ebi.ac.uk/pdbsum/2z15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z15 ProSAT], [https://www.topsan.org/Proteins/RSGI/2z15 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z15 OCA], [https://pdbe.org/2z15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z15 RCSB], [https://www.ebi.ac.uk/pdbsum/2z15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z15 ProSAT], [https://www.topsan.org/Proteins/RSGI/2z15 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/TOB1_HUMAN TOB1_HUMAN]] Anti-proliferative protein that interacts with the erbB-2 receptor tyrosine kinase. May physically and/or functionally interact with protein-tyrosine kinase receptors.
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[https://www.uniprot.org/uniprot/TOB1_HUMAN TOB1_HUMAN] Anti-proliferative protein that interacts with the erbB-2 receptor tyrosine kinase. May physically and/or functionally interact with protein-tyrosine kinase receptors.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Kigawa, T]]
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[[Category: Kigawa T]]
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[[Category: Kishishita, S]]
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[[Category: Kishishita S]]
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[[Category: Murayama, K]]
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[[Category: Murayama K]]
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[[Category: Nishino, A]]
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[[Category: Nishino A]]
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[[Category: Structural genomic]]
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[[Category: Saito K]]
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[[Category: Saito, K]]
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[[Category: Shirouzu M]]
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[[Category: Shirouzu, M]]
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[[Category: Terada T]]
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[[Category: Terada, T]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Human tob1 protein]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Phosphorylation]]
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[[Category: Rsgi]]
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[[Category: Signaling protein]]
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Current revision

Crystal structure of human Tob1 protein

PDB ID 2z15

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