6c6p
From Proteopedia
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<StructureSection load='6c6p' size='340' side='right'caption='[[6c6p]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='6c6p' size='340' side='right'caption='[[6c6p]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[6c6p]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[6c6p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6C6P FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPS:3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE'>CPS</scene>, <scene name='pdbligand=EMV:(2E)-N-({3-[([3,3-bithiophen]-5-yl)methoxy]phenyl}methyl)-N-ethyl-6,6-dimethylhept-2-en-4-yn-1-amine'>EMV</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPS:3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE'>CPS</scene>, <scene name='pdbligand=EMV:(2E)-N-({3-[([3,3-bithiophen]-5-yl)methoxy]phenyl}methyl)-N-ethyl-6,6-dimethylhept-2-en-4-yn-1-amine'>EMV</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6c6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c6p OCA], [https://pdbe.org/6c6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6c6p RCSB], [https://www.ebi.ac.uk/pdbsum/6c6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6c6p ProSAT]</span></td></tr> | |
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- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/ERG1_HUMAN ERG1_HUMAN] Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway. |
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==See Also== | ==See Also== | ||
*[[Epoxidase 3D structures|Epoxidase 3D structures]] | *[[Epoxidase 3D structures|Epoxidase 3D structures]] | ||
*[[Monooxygenase 3D structures|Monooxygenase 3D structures]] | *[[Monooxygenase 3D structures|Monooxygenase 3D structures]] | ||
- | == References == | ||
- | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | + | [[Category: Jin L]] | |
- | [[Category: Jin | + | [[Category: Padyana AK]] |
- | [[Category: Padyana | + | |
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Current revision
Human squalene epoxidase (SQLE, squalene monooxygenase) structure with FAD and NB-598
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