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6ca8

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Current revision (14:27, 13 March 2024) (edit) (undo)
 
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<StructureSection load='6ca8' size='340' side='right'caption='[[6ca8]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
<StructureSection load='6ca8' size='340' side='right'caption='[[6ca8]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6ca8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CA8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6ca8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CA8 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TopoII ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.331&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ca8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ca8 OCA], [https://pdbe.org/6ca8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ca8 RCSB], [https://www.ebi.ac.uk/pdbsum/6ca8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ca8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ca8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ca8 OCA], [https://pdbe.org/6ca8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ca8 RCSB], [https://www.ebi.ac.uk/pdbsum/6ca8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ca8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/Q7Z2D0_PLAFA Q7Z2D0_PLAFA]] Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.[RuleBase:RU362094]
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[https://www.uniprot.org/uniprot/Q7Z2D0_PLAFA Q7Z2D0_PLAFA] Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.[RuleBase:RU362094]
==See Also==
==See Also==
*[[Gyrase 3D Structures|Gyrase 3D Structures]]
*[[Gyrase 3D Structures|Gyrase 3D Structures]]
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*[[Topoisomerase 3D structures|Topoisomerase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Plafa]]
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[[Category: Plasmodium falciparum]]
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[[Category: Kandavelu, P]]
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[[Category: Kandavelu P]]
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[[Category: Kumar, S]]
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[[Category: Kumar S]]
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[[Category: Rathod, P K]]
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[[Category: Rathod PK]]
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[[Category: Dna-binding domain]]
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[[Category: Isomerase]]
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[[Category: Topoisomerase]]
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Current revision

Crystal structure of Plasmodium falciparum topoisomerase II DNA-binding, cleavage and re-ligation domain

PDB ID 6ca8

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