6dzk

<table><tr><td colspan='2'>[[6dzk]] is a 23 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycs2 Mycs2], [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis] and [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis_str._mc2_155 Mycobacterium smegmatis str. mc2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DZK OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6DZK FirstGlance]. <br>

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5o5j|5o5j]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6dzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dzk OCA], [http://pdbe.org/6dzk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dzk RCSB], [http://www.ebi.ac.uk/pdbsum/6dzk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dzk ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/RS11_MYCS2 RS11_MYCS2]] Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome. [[http://www.uniprot.org/uniprot/A0QTK6_MYCS2 A0QTK6_MYCS2]] Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.[HAMAP-Rule:MF_00839] [[http://www.uniprot.org/uniprot/RS7_MYCS2 RS7_MYCS2]] One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA. [[http://www.uniprot.org/uniprot/RS19_MYCS2 RS19_MYCS2]] Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.[HAMAP-Rule:MF_00531] [[http://www.uniprot.org/uniprot/RS14_MYCS2 RS14_MYCS2]] Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.[HAMAP-Rule:MF_00537] [[http://www.uniprot.org/uniprot/RS20_MYCS2 RS20_MYCS2]] Binds directly to 16S ribosomal RNA. [[http://www.uniprot.org/uniprot/RS13_MYCS2 RS13_MYCS2]] Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. [[http://www.uniprot.org/uniprot/RS17_MYCS2 RS17_MYCS2]] One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. [[http://www.uniprot.org/uniprot/A0A0D6J3X3_MYCSM A0A0D6J3X3_MYCSM]] Binds together with S18 to 16S ribosomal RNA.[HAMAP-Rule:MF_00360][SAAS:SAAS00348112] [[http://www.uniprot.org/uniprot/RS3_MYCS2 RS3_MYCS2]] Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation. [[http://www.uniprot.org/uniprot/RS12_MYCS2 RS12_MYCS2]] With S4 and S5 plays an important role in translational accuracy. Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity). [[http://www.uniprot.org/uniprot/RS15_MYCS2 RS15_MYCS2]] One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.[HAMAP-Rule:MF_01343] Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.[HAMAP-Rule:MF_01343] [[http://www.uniprot.org/uniprot/RS181_MYCS2 RS181_MYCS2]] Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.[HAMAP-Rule:MF_00270] [[http://www.uniprot.org/uniprot/RS8_MYCS2 RS8_MYCS2]] One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.[HAMAP-Rule:MF_01302] [[http://www.uniprot.org/uniprot/RS4_MYCS2 RS4_MYCS2]] One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. With S5 and S12 plays an important role in translational accuracy. [[http://www.uniprot.org/uniprot/RS10_MYCS2 RS10_MYCS2]] Involved in the binding of tRNA to the ribosomes. [[http://www.uniprot.org/uniprot/RS5_MYCS2 RS5_MYCS2]] With S4 and S12 plays an important role in translational accuracy.[HAMAP-Rule:MF_01307] Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.[HAMAP-Rule:MF_01307]

 

 

== References ==

<references/>

[[Category: Mycobacterium smegmatis]]

[[Category: Mycobacterium smegmatis str. mc2 155]]

[[Category: Mycs2]]

[[Category: Agrawal, R K]]

[[Category: Derbyshire, K M]]

[[Category: Gray, A G]]

[[Category: Kaushal, P S]]

[[Category: Korripella, R]]

[[Category: Li, Y]]

[[Category: Lin, Q]]

[[Category: Ojha, A]]

[[Category: Sharma, M R]]

[[Category: Wade, J T]]

[[Category: Yang, Y]]

[[Category: Ribosome]]