6ob7

<table><tr><td colspan='2'>[[6ob7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OB7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OB7 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8DZ:(1,4-diazepane-1,4-diyl)di(propane-3,1-diyl)+bis(3,4,5-trimethoxybenzoate)'>8DZ</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ob7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ob7 OCA], [https://pdbe.org/6ob7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ob7 RCSB], [https://www.ebi.ac.uk/pdbsum/6ob7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ob7 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/S29A1_HUMAN S29A1_HUMAN] Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs).

[[Category: Homo sapiens]]

[[Category: Lee S-Y]]

[[Category: Wright NJ]]