6u45

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Current revision (14:56, 13 March 2024) (edit) (undo)
 
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<StructureSection load='6u45' size='340' side='right'caption='[[6u45]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
<StructureSection load='6u45' size='340' side='right'caption='[[6u45]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6u45]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6U45 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6U45 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6u45]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candidatus_Methanoperedens_nitroreducens Candidatus Methanoperedens nitroreducens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6U45 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6U45 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6u45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6u45 OCA], [http://pdbe.org/6u45 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6u45 RCSB], [http://www.ebi.ac.uk/pdbsum/6u45 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6u45 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6u45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6u45 OCA], [https://pdbe.org/6u45 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6u45 RCSB], [https://www.ebi.ac.uk/pdbsum/6u45 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6u45 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A0A062V290_9EURY A0A062V290_9EURY]] Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.[HAMAP-Rule:MF_00054][SAAS:SAAS00384500]
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[https://www.uniprot.org/uniprot/A0A062V290_9EURY A0A062V290_9EURY] Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.[HAMAP-Rule:MF_00054][SAAS:SAAS00384500]
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==See Also==
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*[[Elongation factor 3D structures|Elongation factor 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Candidatus Methanoperedens nitroreducens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ealick, S E]]
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[[Category: Ealick SE]]
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[[Category: Fenwick, M K]]
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[[Category: Fenwick MK]]
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[[Category: Elongation]]
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[[Category: Gtpase]]
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[[Category: Ribosomal translocase]]
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[[Category: Translation]]
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Current revision

Crystal structure of Methanoperedens nitroreducens elongation factor 2 bound to GMPPCP and magnesium

PDB ID 6u45

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