8ite
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of pE301R from African swine fever virus== | |
| - | + | <StructureSection load='8ite' size='340' side='right'caption='[[8ite]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8ite]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/African_swine_fever_virus African swine fever virus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=7drh 7drh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ITE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ITE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ite FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ite OCA], [https://pdbe.org/8ite PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ite RCSB], [https://www.ebi.ac.uk/pdbsum/8ite PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ite ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [https://www.uniprot.org/uniprot/VF301_ASFB7 VF301_ASFB7] Plays a role in the inhibition of host innate immune system by acting as a negatively regulator of type I interferon production. Mechanistically, interacts with and prevents host IRF3 nuclear localization to inhibit its transcriptional activity.<ref>PMID:36099692</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: African swine fever virus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Li YH]] | ||
| + | [[Category: Zhang H]] | ||
Current revision
Crystal structure of pE301R from African swine fever virus
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