3q7u

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Current revision (11:36, 14 March 2024) (edit) (undo)
 
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<StructureSection load='3q7u' size='340' side='right'caption='[[3q7u]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='3q7u' size='340' side='right'caption='[[3q7u]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3q7u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q7U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3q7u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q7U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3okr|3okr]], [[3q80|3q80]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ispD, Rv3582c, MT3688, MTCY06G11.29c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_4-phosphate_cytidylyltransferase 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.60 2.7.7.60] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q7u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7u OCA], [https://pdbe.org/3q7u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q7u RCSB], [https://www.ebi.ac.uk/pdbsum/3q7u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7u ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q7u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7u OCA], [https://pdbe.org/3q7u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q7u RCSB], [https://www.ebi.ac.uk/pdbsum/3q7u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7u ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ISPD_MYCTU ISPD_MYCTU]] Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity).
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[https://www.uniprot.org/uniprot/ISPD_MYCTU ISPD_MYCTU] Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity).
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Bruning, J B]]
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[[Category: Bruning JB]]
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[[Category: Ioerger, T R]]
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[[Category: Ioerger TR]]
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[[Category: Reddy, M C.M]]
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[[Category: Reddy MCM]]
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[[Category: Sacchettini, J C]]
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[[Category: Sacchettini JC]]
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[[Category: Structural genomic]]
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[[Category: Thurman C]]
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[[Category: Thurman, C]]
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[[Category: 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase]]
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[[Category: Rossmann fold]]
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[[Category: Tbsgc]]
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[[Category: Transferase]]
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Current revision

Structure of Mtb 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD) complexed with CTP

PDB ID 3q7u

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