3qu1

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Current revision (11:58, 14 March 2024) (edit) (undo)
 
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<StructureSection load='3qu1' size='340' side='right'caption='[[3qu1]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3qu1' size='340' side='right'caption='[[3qu1]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3qu1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillo_virgola_del_koch"_trevisan_1884 "bacillo virgola del koch" trevisan 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QU1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3qu1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QU1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">def, def2, VC_A0150 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 "Bacillo virgola del Koch" Trevisan 1884])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qu1 OCA], [https://pdbe.org/3qu1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qu1 RCSB], [https://www.ebi.ac.uk/pdbsum/3qu1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qu1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qu1 OCA], [https://pdbe.org/3qu1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qu1 RCSB], [https://www.ebi.ac.uk/pdbsum/3qu1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qu1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/DEF2_VIBCH DEF2_VIBCH]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
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[https://www.uniprot.org/uniprot/DEF2_VIBCH DEF2_VIBCH] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillo virgola del koch trevisan 1884]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Peptide deformylase]]
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[[Category: Vibrio cholerae]]
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[[Category: Anderson, W F]]
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[[Category: Anderson WF]]
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[[Category: Structural genomic]]
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[[Category: Joachimiak A]]
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[[Category: Joachimiak, A]]
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[[Category: Mulligan R]]
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[[Category: Mulligan, R]]
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[[Category: Osipiuk J]]
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[[Category: Osipiuk, J]]
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[[Category: Papazisi L]]
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[[Category: Papazisi, L]]
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[[Category: Csgid]]
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[[Category: Hydrolase]]
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[[Category: Metal binding]]
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[[Category: Metal binding protein]]
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Current revision

Peptide deformylase from Vibrio cholerae

PDB ID 3qu1

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