3s1t

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<StructureSection load='3s1t' size='340' side='right'caption='[[3s1t]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
<StructureSection load='3s1t' size='340' side='right'caption='[[3s1t]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3s1t]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S1T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S1T FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3s1t]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S1T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S1T FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=THR:THREONINE'>THR</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.63&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ask, MT3812, MTV025.057c, Rv3709c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=THR:THREONINE'>THR</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aspartate_kinase Aspartate kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.4 2.7.2.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s1t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s1t OCA], [https://pdbe.org/3s1t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s1t RCSB], [https://www.ebi.ac.uk/pdbsum/3s1t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s1t ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s1t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s1t OCA], [https://pdbe.org/3s1t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s1t RCSB], [https://www.ebi.ac.uk/pdbsum/3s1t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s1t ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/AK_MYCTU AK_MYCTU]] Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.
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[https://www.uniprot.org/uniprot/AK_MYCTU AK_MYCTU] Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aspartate kinase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Mueller-Dieckmann, J]]
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[[Category: Mueller-Dieckmann J]]
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[[Category: Schuldt, L]]
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[[Category: Schuldt L]]
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[[Category: Weiss, M S]]
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[[Category: Weiss MS]]
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[[Category: Act domain]]
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[[Category: Regulatory domain of aspartokinase]]
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[[Category: Threonine binding]]
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[[Category: Transferase]]
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Current revision

Structure of the regulatory domain of aspartokinase (Rv3709c; AK-beta) in complex with threonine from Mycobacterium tuberculosis

PDB ID 3s1t

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