3vfh

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Current revision (14:27, 14 March 2024) (edit) (undo)
 
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<StructureSection load='3vfh' size='340' side='right'caption='[[3vfh]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
<StructureSection load='3vfh' size='340' side='right'caption='[[3vfh]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3vfh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VFH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VFH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3vfh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VFH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VFH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD6:(2R)-5-METHYLIDENE-2-{(1R)-2-OXO-1-[(PHENYLACETYL)AMINO]ETHYL}-5,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC+ACID'>CD6</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.57&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3vff|3vff]], [[4ebi|4ebi]], [[4ebl|4ebl]], [[4ebm|4ebm]], [[4ebn|4ebn]], [[4ebo|4ebo]], [[4ebp|4ebp]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD6:(2R)-5-METHYLIDENE-2-{(1R)-2-OXO-1-[(PHENYLACETYL)AMINO]ETHYL}-5,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC+ACID'>CD6</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaA, blaC, MT2128, MTCY49.07c, Rv2068c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vfh OCA], [https://pdbe.org/3vfh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vfh RCSB], [https://www.ebi.ac.uk/pdbsum/3vfh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vfh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vfh OCA], [https://pdbe.org/3vfh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vfh RCSB], [https://www.ebi.ac.uk/pdbsum/3vfh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vfh ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-lactamase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Mire, J A]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Sacchettini, J C]]
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[[Category: Mire JA]]
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[[Category: Structural genomic]]
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[[Category: Sacchettini JC]]
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[[Category: Acyl-intermediate]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Serine esterase]]
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[[Category: Serine hydrolase]]
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[[Category: Tbsgc]]
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Current revision

BlaC E166A CDC-1 Acyl-Intermediate

PDB ID 3vfh

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