This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3vfh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:27, 14 March 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='3vfh' size='340' side='right'caption='[[3vfh]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
<StructureSection load='3vfh' size='340' side='right'caption='[[3vfh]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3vfh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VFH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VFH FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3vfh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VFH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VFH FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD6:(2R)-5-METHYLIDENE-2-{(1R)-2-OXO-1-[(PHENYLACETYL)AMINO]ETHYL}-5,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC+ACID'>CD6</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.57&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3vff|3vff]], [[4ebi|4ebi]], [[4ebl|4ebl]], [[4ebm|4ebm]], [[4ebn|4ebn]], [[4ebo|4ebo]], [[4ebp|4ebp]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD6:(2R)-5-METHYLIDENE-2-{(1R)-2-OXO-1-[(PHENYLACETYL)AMINO]ETHYL}-5,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC+ACID'>CD6</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaA, blaC, MT2128, MTCY49.07c, Rv2068c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vfh OCA], [https://pdbe.org/3vfh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vfh RCSB], [https://www.ebi.ac.uk/pdbsum/3vfh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vfh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vfh OCA], [https://pdbe.org/3vfh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vfh RCSB], [https://www.ebi.ac.uk/pdbsum/3vfh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vfh ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
==See Also==
==See Also==
Line 15: Line 15:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Beta-lactamase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Mire, J A]]
+
[[Category: Mycobacterium tuberculosis]]
-
[[Category: Sacchettini, J C]]
+
[[Category: Mire JA]]
-
[[Category: Structural genomic]]
+
[[Category: Sacchettini JC]]
-
[[Category: Acyl-intermediate]]
+
-
[[Category: Hydrolase-hydrolase inhibitor complex]]
+
-
[[Category: Serine esterase]]
+
-
[[Category: Serine hydrolase]]
+
-
[[Category: Tbsgc]]
+

Current revision

BlaC E166A CDC-1 Acyl-Intermediate

PDB ID 3vfh

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools