8p0v
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the human Commander complex coiled coils, DENND10 and partial Retriever subcomplex== | |
| - | + | <StructureSection load='8p0v' size='340' side='right'caption='[[8p0v]], [[Resolution|resolution]] 6.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8p0v]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8P0V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8P0V FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.5Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8p0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8p0v OCA], [https://pdbe.org/8p0v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8p0v RCSB], [https://www.ebi.ac.uk/pdbsum/8p0v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8p0v ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/VPS29_HUMAN VPS29_HUMAN] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro).<ref>PMID:15247922</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Huiskonen JT]] | ||
| + | [[Category: Kumpula EP]] | ||
| + | [[Category: Laulumaa S]] | ||
Revision as of 08:19, 20 March 2024
Structure of the human Commander complex coiled coils, DENND10 and partial Retriever subcomplex
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