3wew

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Current revision (08:44, 20 March 2024) (edit) (undo)
 
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<StructureSection load='3wew' size='340' side='right'caption='[[3wew]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='3wew' size='340' side='right'caption='[[3wew]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3wew]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WEW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3wew]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WEW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv0242c, RVBD_0241c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wew OCA], [https://pdbe.org/3wew PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wew RCSB], [https://www.ebi.ac.uk/pdbsum/3wew PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wew ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wew OCA], [https://pdbe.org/3wew PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wew RCSB], [https://www.ebi.ac.uk/pdbsum/3wew PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wew ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HTDX_MYCTU HTDX_MYCTU] Shows trans-enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydratase activity (PubMed:19136596, PubMed:20511508). Displays a broad chain length specificity, with a predilection for the C8 to C12 substrates (PubMed:20511508).<ref>PMID:19136596</ref> <ref>PMID:20511508</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Biswas, R]]
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[[Category: Biswas R]]
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[[Category: Das, A K]]
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[[Category: Das AK]]
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[[Category: Dutta, D]]
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[[Category: Dutta D]]
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[[Category: Dehydratase]]
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[[Category: Hotdog fold]]
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[[Category: Lyase]]
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Current revision

Crystal structure of HtdX (Rv0241c) of Mycobacterium tuberculosis at 2.4 A resolution

PDB ID 3wew

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