1r8i

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[[Image:1r8i.jpg|left|200px]]
[[Image:1r8i.jpg|left|200px]]
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{{Structure
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|PDB= 1r8i |SIZE=350|CAPTION= <scene name='initialview01'>1r8i</scene>, resolution 3.00&Aring;
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The line below this paragraph, containing "STRUCTURE_1r8i", creates the "Structure Box" on the page.
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|SITE=
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|LIGAND= <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene>
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|GENE= trac ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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{{STRUCTURE_1r8i| PDB=1r8i | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1r8i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r8i OCA], [http://www.ebi.ac.uk/pdbsum/1r8i PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1r8i RCSB]</span>
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'''Crystal structure of TraC'''
'''Crystal structure of TraC'''
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[[Category: Yeo, H J.]]
[[Category: Yeo, H J.]]
[[Category: Yuan, Q.]]
[[Category: Yuan, Q.]]
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[[Category: helical bundle]]
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[[Category: Helical bundle]]
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[[Category: trac]]
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[[Category: Trac]]
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[[Category: virb5]]
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[[Category: Virb5]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 07:12:59 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:24:48 2008''
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Revision as of 04:13, 3 May 2008

Image:1r8i.jpg

Template:STRUCTURE 1r8i

Crystal structure of TraC


Overview

Type IV secretion systems mediate intercellular transfer of macro-molecules via a mechanism ancestrally related to that of bacterial conjugation machineries. TraC of the IncN plasmid pKM101 belongs to the VirB5 family of proteins, an essential component of most type IV secretion systems. Here, we present the structure of TraC. VirB5/TraC is a single domain protein, which consists of a three helix bundle and a loose globular appendage. Structure-based site-directed mutagenesis followed by functional studies indicates that VirB5 proteins participate in protein-protein interactions important for pilus assembly and function.

About this Structure

1R8I is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Structural and functional characterization of the VirB5 protein from the type IV secretion system encoded by the conjugative plasmid pKM101., Yeo HJ, Yuan Q, Beck MR, Baron C, Waksman G, Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15947-52. Epub 2003 Dec 12. PMID:14673074 Page seeded by OCA on Sat May 3 07:12:59 2008

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