1fea

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<StructureSection load='1fea' size='340' side='right'caption='[[1fea]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='1fea' size='340' side='right'caption='[[1fea]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1fea]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Crifa Crifa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FEA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1FEA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1fea]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Crithidia_fasciculata Crithidia fasciculata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FEA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FEA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1feb|1feb]], [[1fec|1fec]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5656 CRIFA])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fea OCA], [https://pdbe.org/1fea PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fea RCSB], [https://www.ebi.ac.uk/pdbsum/1fea PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fea ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypanothione-disulfide_reductase Trypanothione-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.12 1.8.1.12] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1fea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fea OCA], [http://pdbe.org/1fea PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1fea RCSB], [http://www.ebi.ac.uk/pdbsum/1fea PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1fea ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TYTR_CRIFA TYTR_CRIFA]] Trypanothione is the parasite analog of glutathione; this enzyme is the equivalent of glutathione reductase.
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[https://www.uniprot.org/uniprot/TYTR_CRIFA TYTR_CRIFA] Trypanothione is the parasite analog of glutathione; this enzyme is the equivalent of glutathione reductase.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Crifa]]
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[[Category: Crithidia fasciculata]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Trypanothione-disulfide reductase]]
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[[Category: Karplus P]]
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[[Category: Karplus, P]]
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[[Category: Strickland C]]
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[[Category: Strickland, C]]
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[[Category: Fad]]
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[[Category: Flavoprotein]]
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[[Category: Nadp]]
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[[Category: Oxidoreductase]]
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[[Category: Redox-active center]]
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Revision as of 10:13, 20 March 2024

UNLIGANDED CRITHIDIA FASCICULATA TRYPANOTHIONE REDUCTASE AT 2.2 ANGSTROM RESOLUTION

PDB ID 1fea

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