8oer
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==MUC5B amino acids 26-1435== | |
| - | + | <StructureSection load='8oer' size='340' side='right'caption='[[8oer]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8oer]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OER OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OER FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | [[Category: Fass | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8oer FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8oer OCA], [https://pdbe.org/8oer PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8oer RCSB], [https://www.ebi.ac.uk/pdbsum/8oer PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8oer ProSAT]</span></td></tr> |
| - | [[Category: Khmelnitsky | + | </table> |
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/MUC5B_HUMAN MUC5B_HUMAN] Diffuse panbronchiolitis;Hypersensitivity pneumonitis;Idiopathic pulmonary fibrosis. Disease susceptibility is associated with variants affecting the gene represented in this entry. A common polymorphism in the promoter of MUC5B is associated with familial interstitial pneumonia and idiopathic pulmonary fibrosis, suggesting that dysregulated MUC5B expression in the lung may be involved in the pathogenesis of pulmonary fibrosis (PubMed:21506741).<ref>PMID:21506741</ref> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MUC5B_HUMAN MUC5B_HUMAN] Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fass D]] | ||
| + | [[Category: Khmelnitsky L]] | ||
Revision as of 10:09, 27 March 2024
MUC5B amino acids 26-1435
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