8pag
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the ectodomain of Norway rat pestivirus E2 glycoprotein== | |
| - | + | <StructureSection load='8pag' size='340' side='right'caption='[[8pag]], [[Resolution|resolution]] 3.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8pag]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Norway_rat_pestivirus Norway rat pestivirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PAG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PAG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pag OCA], [https://pdbe.org/8pag PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pag RCSB], [https://www.ebi.ac.uk/pdbsum/8pag PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pag ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A097NZ77_9FLAV A0A097NZ77_9FLAV] Acts as a cofactor for the NS3 protease activity.[ARBA:ARBA00023576] Packages viral RNA to form a viral nucleocapsid and thereby protects viral RNA. Also plays a role in transcription regulation. Protects the incoming virus against IFN-induced effectors.[ARBA:ARBA00034097] Plays a role in the regulation of viral RNA replication.[ARBA:ARBA00023574] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Norway rat pestivirus]] | ||
| + | [[Category: Aitkenhead H]] | ||
| + | [[Category: EL Omari K]] | ||
| + | [[Category: Stuart DI]] | ||
Revision as of 10:11, 27 March 2024
Crystal structure of the ectodomain of Norway rat pestivirus E2 glycoprotein
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