8tnt
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Epstein-Barr virus gH/gL/gp42 in complex with antibodies F-2-1 and 769C2== | |
| - | + | <StructureSection load='8tnt' size='340' side='right'caption='[[8tnt]], [[Resolution|resolution]] 3.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8tnt]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_4 Human gammaherpesvirus 4] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TNT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tnt OCA], [https://pdbe.org/8tnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tnt RCSB], [https://www.ebi.ac.uk/pdbsum/8tnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tnt ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GH_EBVB9 GH_EBVB9] The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. Fusion of EBV with B-lymphocytes requires the additional receptor-binding protein gp42, which forms a complex with gH/gL. May also be required for virus attachment to epithelial cells.<ref>PMID:11021994</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Human gammaherpesvirus 4]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Board N]] | ||
| + | [[Category: Bu W]] | ||
| + | [[Category: Cohen JI]] | ||
| + | [[Category: Dowdell K]] | ||
| + | [[Category: Hostal A]] | ||
| + | [[Category: Kim J]] | ||
| + | [[Category: Krogmann T]] | ||
| + | [[Category: Kumar A]] | ||
| + | [[Category: Lei Y]] | ||
| + | [[Category: Marcotrigiano J]] | ||
| + | [[Category: Pittaluga S]] | ||
| + | [[Category: Wang Y]] | ||
| + | [[Category: Zhang S]] | ||
Revision as of 10:13, 27 March 2024
Crystal structure of Epstein-Barr virus gH/gL/gp42 in complex with antibodies F-2-1 and 769C2
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Categories: Homo sapiens | Human gammaherpesvirus 4 | Large Structures | Mus musculus | Board N | Bu W | Cohen JI | Dowdell K | Hostal A | Kim J | Krogmann T | Kumar A | Lei Y | Marcotrigiano J | Pittaluga S | Wang Y | Zhang S
