8too

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Current revision (10:13, 27 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8too is ON HOLD until Paper Publication
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==Crystal structure of Epstein-Barr virus gp42 in complex with antibody 4C12==
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<StructureSection load='8too' size='340' side='right'caption='[[8too]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8too]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_4 Human gammaherpesvirus 4] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TOO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TOO FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8too FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8too OCA], [https://pdbe.org/8too PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8too RCSB], [https://www.ebi.ac.uk/pdbsum/8too PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8too ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GP42_EBVB9 GP42_EBVB9] Plays a role in virion attachment to host B-lymphocytes, through binding to leukocyte antigen (HLA) class II and subsequently participates in fusion of the virion with host membranes. May act as a tropism switch that directs fusion with B-lymphocytes and inhibits fusion with epithelial cells.<ref>PMID:12042810</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Human gammaherpesvirus 4]]
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Board N]]
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[[Category: Bu W]]
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[[Category: Cohen JI]]
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[[Category: Dowdell K]]
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[[Category: Hostal A]]
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[[Category: Kim J]]
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[[Category: Krogmann T]]
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[[Category: Kumar A]]
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[[Category: Lei Y]]
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[[Category: Marcotrigiano J]]
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[[Category: Pittaluga S]]
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[[Category: Wang Y]]
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[[Category: Zhang S]]

Current revision

Crystal structure of Epstein-Barr virus gp42 in complex with antibody 4C12

PDB ID 8too

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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