8xv5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "8xv5" [edit=sysop:move=sysop])
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8xv5 is ON HOLD until Paper Publication
+
==Pyridoxamine-bound human SLC19A3==
-
 
+
<StructureSection load='8xv5' size='340' side='right'caption='[[8xv5]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
-
Authors:
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[8xv5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XV5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XV5 FirstGlance]. <br>
-
Description:
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PXM:4-(AMINOMETHYL)-5-(HYDROXYMETHYL)-2-METHYLPYRIDIN-3-OL'>PXM</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xv5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xv5 OCA], [https://pdbe.org/8xv5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xv5 RCSB], [https://www.ebi.ac.uk/pdbsum/8xv5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xv5 ProSAT]</span></td></tr>
 +
</table>
 +
== Disease ==
 +
[https://www.uniprot.org/uniprot/S19A3_HUMAN S19A3_HUMAN] Thiamine-responsive encephalopathy;Infantile spasms-psychomotor retardation-progressive brain atrophy-basal ganglia disease syndrome;Biotin-thiamine-responsive basal ganglia disease. The disease is caused by variants affecting the gene represented in this entry.
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/S19A3_HUMAN S19A3_HUMAN] Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism (PubMed:11731220, PubMed:33008889, PubMed:35512554, PubMed:35724964). Has no folate transport activity (PubMed:11731220). Mediates H(+)-dependent pyridoxine transport (PubMed:33008889, PubMed:35512554, PubMed:35724964, PubMed:36456177).<ref>PMID:11731220</ref> <ref>PMID:33008889</ref> <ref>PMID:35512554</ref> <ref>PMID:35724964</ref> <ref>PMID:36456177</ref> [https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Escherichia coli]]
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Dang Y]]
 +
[[Category: Wang GP]]
 +
[[Category: Zhang Z]]

Revision as of 10:15, 27 March 2024

Pyridoxamine-bound human SLC19A3

PDB ID 8xv5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/8xv5"
Personal tools