5xal

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:17, 27 March 2024) (edit) (undo)
 
Line 1: Line 1:
==Y99F mutant of Thermus thermophilus HB8 thymidylate kinase==
==Y99F mutant of Thermus thermophilus HB8 thymidylate kinase==
-
<StructureSection load='5xal' size='340' side='right' caption='[[5xal]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
+
<StructureSection load='5xal' size='340' side='right'caption='[[5xal]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5xal]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XAL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XAL FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5xal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XAL FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5xak|5xak]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tmk, TTHA1607 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xal OCA], [https://pdbe.org/5xal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xal RCSB], [https://www.ebi.ac.uk/pdbsum/5xal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xal ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xal OCA], [http://pdbe.org/5xal PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xal RCSB], [http://www.ebi.ac.uk/pdbsum/5xal PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xal ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/KTHY_THET8 KTHY_THET8]] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
+
[https://www.uniprot.org/uniprot/KTHY_THET8 KTHY_THET8] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
 +
 
 +
==See Also==
 +
*[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Thet8]]
+
[[Category: Large Structures]]
-
[[Category: DTMP kinase]]
+
[[Category: Thermus thermophilus HB8]]
-
[[Category: Chaudhary, S K]]
+
[[Category: Chaudhary SK]]
-
[[Category: Jeyakanthan, J]]
+
[[Category: Jeyakanthan J]]
-
[[Category: Sekar, K]]
+
[[Category: Sekar K]]
-
[[Category: Nucleotide monophosphate kinase]]
+
-
[[Category: Transferase]]
+

Current revision

Y99F mutant of Thermus thermophilus HB8 thymidylate kinase

PDB ID 5xal

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools