5ylo

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Current revision (10:23, 27 March 2024) (edit) (undo)
 
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<StructureSection load='5ylo' size='340' side='right'caption='[[5ylo]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
<StructureSection load='5ylo' size='340' side='right'caption='[[5ylo]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ylo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YLO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YLO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ylo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YLO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YLO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.39&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA4980 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ylo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ylo OCA], [http://pdbe.org/5ylo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ylo RCSB], [http://www.ebi.ac.uk/pdbsum/5ylo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ylo ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ylo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ylo OCA], [https://pdbe.org/5ylo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ylo RCSB], [https://www.ebi.ac.uk/pdbsum/5ylo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ylo ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/Q9HUI5_PSEAE Q9HUI5_PSEAE]
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Gene PA4980 from Pseudomonas aeruginosa encodes a putative enoyl-coenzyme A hydratase/isomerase that is associated with the function of the bio fi lm dispersion-inducing signal molecule cis-2-decenoic acid. To elucidate the role of PA4980 in cis-2-decenoic acid biosynthesis, we reported the crystal structure of its protein product at 2.39 A. The structural analysis and substrate binding prediction suggest that it acts as a monofunctional enoyl-coenzyme A isomerase, implicating an alternative pathway of the cis-2-decenoic acid synthesis.
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Structural characterization of a Delta(3), Delta(2)-enoyl-CoA isomerase from Pseudomonas aeruginosa: implications for its involvement in unsaturated fatty acid metabolism.,Liu L, Li T, Peng CT, Sun CZ, Li CC, Xiao QJ, He LH, Wang NY, Song YJ, Zhu YB, Li H, Kang M, Tang H, Xiong X, Bao R J Biomol Struct Dyn. 2018 Jul 27:1-22. doi: 10.1080/07391102.2018.1495102. PMID:30052139<ref>PMID:30052139</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 5ylo" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pseae]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Bao, R]]
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[[Category: Bao R]]
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[[Category: He, L H]]
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[[Category: He LH]]
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[[Category: Li, C C]]
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[[Category: Li CC]]
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[[Category: Li, T]]
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[[Category: Li T]]
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[[Category: Liu, L]]
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[[Category: Liu L]]
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[[Category: Peng, C T]]
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[[Category: Peng CT]]
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[[Category: Wang, N Y]]
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[[Category: Wang NY]]
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[[Category: Xiao, Q J]]
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[[Category: Xiao QJ]]
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[[Category: Enoyl-coa hydratase activity]]
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[[Category: Fatty acid beta-oxidation]]
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[[Category: Hydrolase]]
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Current revision

Structural of Pseudomonas aeruginosa PA4980

PDB ID 5ylo

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