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5z33

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Current revision (10:26, 27 March 2024) (edit) (undo)
 
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<StructureSection load='5z33' size='340' side='right'caption='[[5z33]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
<StructureSection load='5z33' size='340' side='right'caption='[[5z33]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5z33]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z33 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Z33 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5z33]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyricularia_oryzae_P131 Pyricularia oryzae P131]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z33 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Z33 FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5z33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z33 OCA], [http://pdbe.org/5z33 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5z33 RCSB], [http://www.ebi.ac.uk/pdbsum/5z33 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5z33 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5z33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z33 OCA], [https://pdbe.org/5z33 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5z33 RCSB], [https://www.ebi.ac.uk/pdbsum/5z33 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5z33 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MPS1_MAGO7 MPS1_MAGO7] Mitogen-activated protein kinase; part of the MCK1-MKK2-MPS1 MAP kinase (MAPK) signal transduction cascade that is essential for cell wall integrity and plant infection, but not for plant defense responses (PubMed:9770551, PubMed:18344407, PubMed:22321443, PubMed:28799700, PubMed:28424497). Beside its role in pathogenesis, the MPS1 cascade is active in conidiation and cellular stress responses (PubMed:9770551). Targets downstream of the MPS1-MAPK pathway include transcription factors MIG1 and SWI6, as well as GSK1 and MPG1 (PubMed:18344407, PubMed:22321443, PubMed:28424497).<ref>PMID:18344407</ref> <ref>PMID:22321443</ref> <ref>PMID:28424497</ref> <ref>PMID:28799700</ref> <ref>PMID:9770551</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Mitogen-activated protein kinase]]
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[[Category: Pyricularia oryzae P131]]
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[[Category: Liu, J F]]
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[[Category: Liu JF]]
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[[Category: Zhang, G Z]]
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[[Category: Zhang GZ]]
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[[Category: Zhou, F]]
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[[Category: Zhou F]]
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[[Category: Magnaporthe oryzae]]
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[[Category: Mapk]]
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[[Category: Mps1]]
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[[Category: Phosphorylation]]
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[[Category: Transferase]]
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Current revision

Crystal structure of Mitogen-activated Protein Kinase Mps1 in Magnaporthe oryzae

PDB ID 5z33

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