6ire

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Current revision (10:34, 27 March 2024) (edit) (undo)
 
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====
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==Complex structure of INAD PDZ45 and NORPA CC-PBM==
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<StructureSection load='6ire' size='340' side='right'caption='[[6ire]]' scene=''>
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<StructureSection load='6ire' size='340' side='right'caption='[[6ire]], [[Resolution|resolution]] 3.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6ire]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IRE FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ire FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ire OCA], [http://pdbe.org/6ire PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ire RCSB], [http://www.ebi.ac.uk/pdbsum/6ire PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ire ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.25&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ire FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ire OCA], [https://pdbe.org/6ire PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ire RCSB], [https://www.ebi.ac.uk/pdbsum/6ire PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ire ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PIPA_DROME PIPA_DROME] The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (By similarity). Essential component of the phototransduction pathway (PubMed:2457447). Essential downstream component of a hh-signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required for the activation of Cad99C and consequently Cad99C-dependent endosome formation, which is essential for the Duox-dependent production of reactive oxygen species (ROS) in response to intestinal bacterial infection (PubMed:25639794).[UniProtKB:Q9P212]<ref>PMID:2457447</ref> <ref>PMID:25639794</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Deng X]]
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[[Category: Li J]]
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[[Category: Liu W]]
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[[Category: Ye F]]
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[[Category: Zhang M]]

Current revision

Complex structure of INAD PDZ45 and NORPA CC-PBM

PDB ID 6ire

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