6iue

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Current revision (10:35, 27 March 2024) (edit) (undo)
 
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<StructureSection load='6iue' size='340' side='right'caption='[[6iue]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='6iue' size='340' side='right'caption='[[6iue]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6iue]] is a 24 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IUE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IUE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6iue]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IUE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IUE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.901&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6iue FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iue OCA], [http://pdbe.org/6iue PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6iue RCSB], [http://www.ebi.ac.uk/pdbsum/6iue PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6iue ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6iue FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iue OCA], [https://pdbe.org/6iue PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6iue RCSB], [https://www.ebi.ac.uk/pdbsum/6iue PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6iue ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
 
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== Publication Abstract from PubMed ==
 
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Numerous applications of metal ion-mediated base pairs (metallo-base pairs) to nucleic acid-based nanodevices and genetic code expansion have extensively been studied. Many of these metallo-base pairs are formed in DNA and RNA duplexes containing Watson-Crick base pairs. Recently, a crystal structure of a metal-DNA nanowires with uninterrupted one-dimensional silver array has been reported. Herein, we have determined a crystal structure of a novel DNA helical wire containing Hg(II)-mediated T:T and T:G base pairs and water-mediated C:C base pairs. The Hg-DNA wire contains no Watson-Crick base pair. The crystals of the Hg-DNA wire, the first DNA wire structure driven by Hg(II) ions, were obtained by mixing a short oligonucleotide d(TTTGC) and Hg(II) ions. This study demonstrates potentials of metallo-DNA to form various structural components which can be used for functional nanodevices.
 
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Novel DNA helical wire containing Hg(II) mediated T:T and T:G pairs.,Ono A, Kanazawa H, Ito H, Goto M, Nakamura K, Saneyoshi H, Kondo J Angew Chem Int Ed Engl. 2019 Sep 10. doi: 10.1002/anie.201910029. PMID:31507027<ref>PMID:31507027</ref>
 
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 
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</div>
 
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<div class="pdbe-citations 6iue" style="background-color:#fffaf0;"></div>
 
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== References ==
 
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<references/>
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Goto, M]]
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[[Category: Synthetic construct]]
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[[Category: Ito, H]]
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[[Category: Goto M]]
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[[Category: Kanazawa, H]]
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[[Category: Ito H]]
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[[Category: Kondo, J]]
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[[Category: Kanazawa H]]
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[[Category: Nakamura, K]]
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[[Category: Kondo J]]
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[[Category: Ono, A]]
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[[Category: Nakamura K]]
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[[Category: Saneyoshi, H]]
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[[Category: Ono A]]
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[[Category: Dna]]
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[[Category: Saneyoshi H]]
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[[Category: Mercury]]
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[[Category: Metallo-base pair]]
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[[Category: Nanowire]]
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Current revision

DNA helical wire containing Hg(II)

PDB ID 6iue

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