6iue
From Proteopedia
(Difference between revisions)
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<StructureSection load='6iue' size='340' side='right'caption='[[6iue]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='6iue' size='340' side='right'caption='[[6iue]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[6iue]] is a 24 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IUE OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6iue]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IUE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IUE FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.901Å</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6iue FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iue OCA], [https://pdbe.org/6iue PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6iue RCSB], [https://www.ebi.ac.uk/pdbsum/6iue PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6iue ProSAT]</span></td></tr> | ||
</table> | </table> | ||
- | <div style="background-color:#fffaf0;"> | ||
- | == Publication Abstract from PubMed == | ||
- | Numerous applications of metal ion-mediated base pairs (metallo-base pairs) to nucleic acid-based nanodevices and genetic code expansion have extensively been studied. Many of these metallo-base pairs are formed in DNA and RNA duplexes containing Watson-Crick base pairs. Recently, a crystal structure of a metal-DNA nanowires with uninterrupted one-dimensional silver array has been reported. Herein, we have determined a crystal structure of a novel DNA helical wire containing Hg(II)-mediated T:T and T:G base pairs and water-mediated C:C base pairs. The Hg-DNA wire contains no Watson-Crick base pair. The crystals of the Hg-DNA wire, the first DNA wire structure driven by Hg(II) ions, were obtained by mixing a short oligonucleotide d(TTTGC) and Hg(II) ions. This study demonstrates potentials of metallo-DNA to form various structural components which can be used for functional nanodevices. | ||
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- | Novel DNA helical wire containing Hg(II) mediated T:T and T:G pairs.,Ono A, Kanazawa H, Ito H, Goto M, Nakamura K, Saneyoshi H, Kondo J Angew Chem Int Ed Engl. 2019 Sep 10. doi: 10.1002/anie.201910029. PMID:31507027<ref>PMID:31507027</ref> | ||
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- | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
- | </div> | ||
- | <div class="pdbe-citations 6iue" style="background-color:#fffaf0;"></div> | ||
- | == References == | ||
- | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: Goto | + | [[Category: Synthetic construct]] |
- | [[Category: Ito | + | [[Category: Goto M]] |
- | [[Category: Kanazawa | + | [[Category: Ito H]] |
- | [[Category: Kondo | + | [[Category: Kanazawa H]] |
- | [[Category: Nakamura | + | [[Category: Kondo J]] |
- | [[Category: Ono | + | [[Category: Nakamura K]] |
- | [[Category: Saneyoshi | + | [[Category: Ono A]] |
- | + | [[Category: Saneyoshi H]] | |
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Current revision
DNA helical wire containing Hg(II)
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Categories: Large Structures | Synthetic construct | Goto M | Ito H | Kanazawa H | Kondo J | Nakamura K | Ono A | Saneyoshi H