6jde

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Current revision (10:37, 27 March 2024) (edit) (undo)
 
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<StructureSection load='6jde' size='340' side='right'caption='[[6jde]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='6jde' size='340' side='right'caption='[[6jde]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6jde]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JDE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JDE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6jde]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JDE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JDE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">radD, yejH, yejI, yejJ, b2184, JW2172 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jde OCA], [https://pdbe.org/6jde PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jde RCSB], [https://www.ebi.ac.uk/pdbsum/6jde PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jde ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jde OCA], [http://pdbe.org/6jde PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jde RCSB], [http://www.ebi.ac.uk/pdbsum/6jde PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jde ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RADD_ECOLI RADD_ECOLI]] May be a helicase. In combination with RadA is important in repair of double-strand DNA breaks (DSB) (PubMed:25425430, PubMed:25484163).<ref>PMID:25425430</ref> <ref>PMID:25484163</ref>
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[https://www.uniprot.org/uniprot/RADD_ECOLI RADD_ECOLI] May be a helicase. In combination with RadA is important in repair of double-strand DNA breaks (DSB) (PubMed:25425430, PubMed:25484163).<ref>PMID:25425430</ref> <ref>PMID:25484163</ref>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The helicase superfamily 2 (SF2) proteins are involved in essentially every step in DNA and RNA metabolism. The radD (yejH) gene, which belongs to SF2, plays an important role in DNA repair. The RadD protein includes all seven conserved SF2 motifs and has shown ATPase activity. Here, we first reported the structure of RadD from Escherichia coli containing two RecA-like domains, a zinc finger motif, and a C-terminal domain. Based on the structure of RadD and other SF2 proteins, we then built a model of the RedD-ATP complex.
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Crystal structure of a novel ATPase RadD from Escherichia coli.,Kuang X, Tang Q, Liu YP, Yan XX, Xu W Proteins. 2019 Apr 29. doi: 10.1002/prot.25704. PMID:31035307<ref>PMID:31035307</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 6jde" style="background-color:#fffaf0;"></div>
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== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: DNA helicase]]
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[[Category: Escherichia coli K-12]]
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[[Category: Ecoli]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Tang, Q]]
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[[Category: Tang Q]]
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[[Category: Yan, X X]]
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[[Category: Yan XX]]
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[[Category: Dna repair protein]]
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[[Category: Hydrolase]]
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Current revision

crystal structure of a DNA repair protein

PDB ID 6jde

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