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6job

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Current revision (10:38, 27 March 2024) (edit) (undo)
 
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<StructureSection load='6job' size='340' side='right'caption='[[6job]], [[Resolution|resolution]] 2.93&Aring;' scene=''>
<StructureSection load='6job' size='340' side='right'caption='[[6job]], [[Resolution|resolution]] 2.93&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6job]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JOB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JOB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6job]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JOB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JOB FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Hybrid , X-ray diffraction , X-ray solution scattering, [[Resolution|Resolution]] 2.93&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6job FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6job OCA], [http://pdbe.org/6job PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6job RCSB], [http://www.ebi.ac.uk/pdbsum/6job PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6job ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6job FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6job OCA], [https://pdbe.org/6job PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6job RCSB], [https://www.ebi.ac.uk/pdbsum/6job PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6job ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
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[https://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
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==See Also==
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*[[Ferritin 3D structures|Ferritin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ferroxidase]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lv, C]]
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[[Category: Lv C]]
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[[Category: Wang, H]]
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[[Category: Wang H]]
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[[Category: Zhang, T]]
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[[Category: Zhang T]]
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[[Category: Zhao, G]]
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[[Category: Zhao G]]
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[[Category: Zheng, B W]]
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[[Category: Zheng BW]]
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[[Category: Zhou, K]]
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[[Category: Zhou K]]
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[[Category: 2d ordered array]]
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[[Category: 3d cubic-like array]]
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[[Category: Amyloidogenic motif]]
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[[Category: Oxidoreductase]]
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[[Category: Ph-manipulated]]
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[[Category: Protein nanocage]]
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[[Category: Protein surfaces redesign]]
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Current revision

Ferritin variant with "GMG" motif

PDB ID 6job

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