6l7q

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Current revision (10:45, 27 March 2024) (edit) (undo)
 
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<StructureSection load='6l7q' size='340' side='right'caption='[[6l7q]], [[Resolution|resolution]] 1.16&Aring;' scene=''>
<StructureSection load='6l7q' size='340' side='right'caption='[[6l7q]], [[Resolution|resolution]] 1.16&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6l7q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyryc Pyryc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L7Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L7Q FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6l7q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_yayanosii_CH1 Pyrococcus yayanosii CH1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L7Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L7Q FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PYCH_01220 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=529709 PYRYC])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.16&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l7q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l7q OCA], [https://pdbe.org/6l7q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l7q RCSB], [https://www.ebi.ac.uk/pdbsum/6l7q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l7q ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l7q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l7q OCA], [https://pdbe.org/6l7q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l7q RCSB], [https://www.ebi.ac.uk/pdbsum/6l7q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l7q ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/F8AFT0_PYRYC F8AFT0_PYRYC]
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We report the crystal structure of PYCH_01220, a hypothetical protein in Pyrococcus yayanosii CH1. This protein is composed of two domains, named Domain A and Domain B. While Domain B is not significantly homologous to known protein structures, Domain A is structurally analogous to the C-terminal ribonuclease domain of Escherichia coli colicin D. Domain A has a positively charged surface patch rendered by 13 basic residues, eight arginine or lysine residues of which are evolutionarily conserved. Electrophoretic mobility shift assays showed that PYCH_01220 binds to DNA, and charge-inversion mutations on this patch negatively affect the DNA binding, suggesting that the function of PYCH_01220 might involve nucleic acid-binding via the positively charged patch. This article is protected by copyright. All rights reserved.
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Crystal structure of PYCH_01220 from Pyrococcus yayanosii potentially involved in binding nucleic acid.,Noh H, Jeon JH, Kim YG, Oh BH Proteins. 2020 Nov 25. doi: 10.1002/prot.26029. PMID:33236809<ref>PMID:33236809</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 6l7q" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pyryc]]
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[[Category: Pyrococcus yayanosii CH1]]
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[[Category: Jeon, J H]]
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[[Category: Jeon J-H]]
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[[Category: Noh, H]]
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[[Category: Noh H]]
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[[Category: Oh, B H]]
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[[Category: Oh B-H]]
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[[Category: Cytosolic protein]]
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[[Category: Hypothetical protein]]
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[[Category: Unknown function]]
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Current revision

Crystal structure of a hypothetical protein PYCH_01220 derived from Pyrococcus yayanosii

PDB ID 6l7q

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