6l8o

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Current revision (10:45, 27 March 2024) (edit) (undo)
 
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<StructureSection load='6l8o' size='340' side='right'caption='[[6l8o]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
<StructureSection load='6l8o' size='340' side='right'caption='[[6l8o]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6l8o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_sphaerica Candida sphaerica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L8O OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6L8O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6l8o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Kluyveromyces_lactis_NRRL_Y-1140 Kluyveromyces lactis NRRL Y-1140]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L8O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L8O FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[6l8n|6l8n]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RAD5, KLLA0F17479g ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284590 Candida sphaerica])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l8o OCA], [https://pdbe.org/6l8o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l8o RCSB], [https://www.ebi.ac.uk/pdbsum/6l8o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l8o ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6l8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l8o OCA], [http://pdbe.org/6l8o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6l8o RCSB], [http://www.ebi.ac.uk/pdbsum/6l8o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6l8o ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RAD5_KLULA RAD5_KLULA]] Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity).
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[https://www.uniprot.org/uniprot/RAD5_KLULA RAD5_KLULA] Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Candida sphaerica]]
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[[Category: Kluyveromyces lactis NRRL Y-1140]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Shen, M]]
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[[Category: Shen M]]
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[[Category: Xiang, S]]
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[[Category: Xiang S]]
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[[Category: Dna binding protein]]
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[[Category: Dna damage tolerance]]
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[[Category: Helicase]]
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[[Category: Snf2 family]]
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Current revision

Crystal structure of the K. lactis Rad5 (Hg-derivative)

PDB ID 6l8o

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