6m3f

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==Crystal structure of the mouse endonuclease EndoG(H138A/C110A), space group P212121==
==Crystal structure of the mouse endonuclease EndoG(H138A/C110A), space group P212121==
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<StructureSection load='6m3f' size='340' side='right'caption='[[6m3f]]' scene=''>
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<StructureSection load='6m3f' size='340' side='right'caption='[[6m3f]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M3F OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6M3F FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6m3f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6M3F FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6m3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m3f OCA], [http://pdbe.org/6m3f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6m3f RCSB], [http://www.ebi.ac.uk/pdbsum/6m3f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6m3f ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6m3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m3f OCA], [https://pdbe.org/6m3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6m3f RCSB], [https://www.ebi.ac.uk/pdbsum/6m3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6m3f ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NUCG_MOUSE NUCG_MOUSE] Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA (By similarity).
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==See Also==
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Mus musculus]]
[[Category: Park KH]]
[[Category: Park KH]]
[[Category: Woo EJ]]
[[Category: Woo EJ]]

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Crystal structure of the mouse endonuclease EndoG(H138A/C110A), space group P212121

PDB ID 6m3f

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