7bp3
From Proteopedia
(Difference between revisions)
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| - | == | + | ==Cryo-EM structure of the human MCT2== |
| - | <StructureSection load='7bp3' size='340' side='right'caption='[[7bp3]]' scene=''> | + | <StructureSection load='7bp3' size='340' side='right'caption='[[7bp3]], [[Resolution|resolution]] 3.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BP3 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7bp3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BP3 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bp3 OCA], [https://pdbe.org/7bp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bp3 RCSB], [https://www.ebi.ac.uk/pdbsum/7bp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bp3 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bp3 OCA], [https://pdbe.org/7bp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bp3 RCSB], [https://www.ebi.ac.uk/pdbsum/7bp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bp3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MOT2_HUMAN MOT2_HUMAN] Proton-coupled monocarboxylate symporter. Catalyzes the rapid transport across the plasma membrane of monocarboxylates such as L-lactate, pyruvate and ketone bodies, acetoacetate, beta-hydroxybutyrate and acetate (PubMed:9786900, PubMed:32415067). Dimerization is functionally required and both subunits work cooperatively in transporting substrate (PubMed:32415067).<ref>PMID:32415067</ref> <ref>PMID:9786900</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Guo J]] |
| + | [[Category: Jin Q]] | ||
| + | [[Category: Ye S]] | ||
| + | [[Category: Zhang B]] | ||
| + | [[Category: Zhang X]] | ||
Current revision
Cryo-EM structure of the human MCT2
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Categories: Homo sapiens | Large Structures | Guo J | Jin Q | Ye S | Zhang B | Zhang X
