7ck8
From Proteopedia
(Difference between revisions)
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==Crystal structure of human ferritin heavy chain mutant C90S/C102S/C130S== | ==Crystal structure of human ferritin heavy chain mutant C90S/C102S/C130S== | ||
| - | <StructureSection load='7ck8' size='340' side='right'caption='[[7ck8]]' scene=''> | + | <StructureSection load='7ck8' size='340' side='right'caption='[[7ck8]], [[Resolution|resolution]] 1.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CK8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CK8 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7ck8]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CK8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CK8 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ck8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ck8 OCA], [https://pdbe.org/7ck8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ck8 RCSB], [https://www.ebi.ac.uk/pdbsum/7ck8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ck8 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ck8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ck8 OCA], [https://pdbe.org/7ck8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ck8 RCSB], [https://www.ebi.ac.uk/pdbsum/7ck8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ck8 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Ferritin 3D structures|Ferritin 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Chen X]] | [[Category: Chen X]] | ||
Current revision
Crystal structure of human ferritin heavy chain mutant C90S/C102S/C130S
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Categories: Homo sapiens | Large Structures | Chen X | Fan K | Jiang B | Yan X
