1h3z
From Proteopedia
(Difference between revisions)
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==Solution structure of a PWWP domain from Schizosaccharomyces Pombe== | ==Solution structure of a PWWP domain from Schizosaccharomyces Pombe== | ||
| - | <StructureSection load='1h3z' size='340' side='right'caption='[[1h3z | + | <StructureSection load='1h3z' size='340' side='right'caption='[[1h3z]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1h3z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1h3z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H3Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H3Z FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h3z OCA], [https://pdbe.org/1h3z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h3z RCSB], [https://www.ebi.ac.uk/pdbsum/1h3z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h3z ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h3z OCA], [https://pdbe.org/1h3z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h3z RCSB], [https://www.ebi.ac.uk/pdbsum/1h3z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h3z ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PDP2_SCHPO PDP2_SCHPO] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h3z ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h3z ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | The PWWP domain is a ubiquitous eukaryotic protein module characterised by a region of sequence similarity of approximately 80 amino acids containing a highly conserved PWWP motif. It is frequently found in proteins associated with chromatin. We have determined the structure of a PWWP domain from the S. pombe protein SPBC215.07c using NMR spectroscopy. The structure is composed of a five stranded beta barrel followed by two alpha helices. Comparison to the recently reported structure of a homologous domain from the mammalian DNA methyltransferase Dnmt3b reveals substantial differences both in the C-terminal helical region and in the PWWP motif. | ||
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| - | Structural variation in PWWP domains.,Slater LM, Allen MD, Bycroft M J Mol Biol. 2003 Jul 11;330(3):571-6. PMID:12842472<ref>PMID:12842472</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 1h3z" style="background-color:#fffaf0;"></div> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Cbs 356]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Schizosaccharomyces pombe]] |
| - | [[Category: | + | [[Category: Allen MD]] |
| - | [[Category: | + | [[Category: Bycroft M]] |
| - | [[Category: | + | [[Category: Slater LM]] |
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| - | + | ||
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Revision as of 11:27, 27 March 2024
Solution structure of a PWWP domain from Schizosaccharomyces Pombe
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