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1rec

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[[Image:1rec.gif|left|200px]]
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{{Structure
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{{STRUCTURE_1rec| PDB=1rec | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rec OCA], [http://www.ebi.ac.uk/pdbsum/1rec PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1rec RCSB]</span>
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'''THREE-DIMENSIONAL STRUCTURE OF RECOVERIN, A CALCIUM SENSOR IN VISION'''
'''THREE-DIMENSIONAL STRUCTURE OF RECOVERIN, A CALCIUM SENSOR IN VISION'''
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[[Category: Stryer, L.]]
[[Category: Stryer, L.]]
[[Category: Zozulya, S.]]
[[Category: Zozulya, S.]]
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[[Category: calcium-binding protein]]
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[[Category: Calcium-binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 07:23:36 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:26:57 2008''
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Revision as of 04:23, 3 May 2008

Image:1rec.gif

Template:STRUCTURE 1rec

THREE-DIMENSIONAL STRUCTURE OF RECOVERIN, A CALCIUM SENSOR IN VISION


Overview

Recoverin, a recently discovered member of the EF hand superfamily, serves as a calcium sensor in vision. We report here the crystal structure of recombinant unmyristoylated recoverin at 1.9 A resolution. The four EF hands of the protein are arranged in a compact array that contrasts with the dumbbell shape of calmodulin and troponin C. A calcium ion is bound to EF hand 3, while EF hand 2 can bind samarium but not calcium in this crystal form. The other two EF hands have novel structural features that prevent or impair calcium binding. A concave hydrophobic surface formed by EF hands 1 and 2 may participate in the read out of calcium signals by recoverin and its homologs.

About this Structure

1REC is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Three-dimensional structure of recoverin, a calcium sensor in vision., Flaherty KM, Zozulya S, Stryer L, McKay DB, Cell. 1993 Nov 19;75(4):709-16. PMID:8242744 Page seeded by OCA on Sat May 3 07:23:36 2008

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