Cefepime

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Cefepime is a fourth-generation [[cephalosporin]] antibiotic. Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria, with greater activity against both types of organism than third-generation agents. A 2007 meta-analysis suggested when data of trials were combined, mortality was increased in people treated with cefepime compared with other β-lactam antibiotics. <ref name="a1">PMID:17448937</ref> [https://en.wikipedia.org/wiki/Cefepime Cefepime].
Cefepime is a fourth-generation [[cephalosporin]] antibiotic. Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria, with greater activity against both types of organism than third-generation agents. A 2007 meta-analysis suggested when data of trials were combined, mortality was increased in people treated with cefepime compared with other β-lactam antibiotics. <ref name="a1">PMID:17448937</ref> [https://en.wikipedia.org/wiki/Cefepime Cefepime].
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<scene name='10/1040142/Cv/2'>Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae in complex with Cefepime</scene> ([[5oj0]]).
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== References ==
== References ==
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Revision as of 13:33, 1 April 2024

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References

  1. Yahav D, Paul M, Fraser A, Sarid N, Leibovici L. Efficacy and safety of cefepime: a systematic review and meta-analysis. Lancet Infect Dis. 2007 May;7(5):338-48. PMID:17448937 doi:10.1016/S1473-3099(07)70109-3

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Alexander Berchansky

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