8rtz

Structural highlights

Function

FTSI_ECOLI Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum (PubMed:1103132, PubMed:6450748, PubMed:9614966, PubMed:3531167, PubMed:7030331). Required for localization of FtsN (PubMed:9282742).^{[1] [2] [3] [4] [5] [6]}

References

1. ↑ Spratt BG. Distinct penicillin binding proteins involved in the division, elongation, and shape of Escherichia coli K12. Proc Natl Acad Sci U S A. 1975 Aug;72(8):2999-3003. PMID:1103132
2. ↑ Pisabarro AG, Prats R, Vaquez D, Rodriguez-Tebar A. Activity of penicillin-binding protein 3 from Escherichia coli. J Bacteriol. 1986 Oct;168(1):199-206. doi: 10.1128/jb.168.1.199-206.1986. PMID:3531167 doi:http://dx.doi.org/10.1128/jb.168.1.199-206.1986
3. ↑ Botta GA, Park JT. Evidence for involvement of penicillin-binding protein 3 in murein synthesis during septation but not during cell elongation. J Bacteriol. 1981 Jan;145(1):333-40. doi: 10.1128/jb.145.1.333-340.1981. PMID:6450748 doi:http://dx.doi.org/10.1128/jb.145.1.333-340.1981
4. ↑ Ishino F, Matsuhashi M. Peptidoglycan synthetic enzyme activities of highly purified penicillin-binding protein 3 in Escherichia coli: a septum-forming reaction sequence. Biochem Biophys Res Commun. 1981 Aug 14;101(3):905-11. doi:, 10.1016/0006-291x(81)91835-0. PMID:7030331 doi:http://dx.doi.org/10.1016/0006-291x(81)91835-0
5. ↑ Addinall SG, Cao C, Lutkenhaus J. FtsN, a late recruit to the septum in Escherichia coli. Mol Microbiol. 1997 Jul;25(2):303-9. doi: 10.1046/j.1365-2958.1997.4641833.x. PMID:9282742 doi:http://dx.doi.org/10.1046/j.1365-2958.1997.4641833.x
6. ↑ Nguyen-Disteche M, Fraipont C, Buddelmeijer N, Nanninga N. The structure and function of Escherichia coli penicillin-binding protein 3. Cell Mol Life Sci. 1998 Apr;54(4):309-16. doi: 10.1007/s000180050157. PMID:9614966 doi:http://dx.doi.org/10.1007/s000180050157