3n7x
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3n7x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Decapod_penstyldensovirus_1 Decapod penstyldensovirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N7X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N7X FirstGlance]. <br> | <table><tr><td colspan='2'>[[3n7x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Decapod_penstyldensovirus_1 Decapod penstyldensovirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N7X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N7X FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n7x OCA], [https://pdbe.org/3n7x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n7x RCSB], [https://www.ebi.ac.uk/pdbsum/3n7x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n7x ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n7x OCA], [https://pdbe.org/3n7x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n7x RCSB], [https://www.ebi.ac.uk/pdbsum/3n7x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n7x ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/Q9E2G5_9VIRU Q9E2G5_9VIRU] | [https://www.uniprot.org/uniprot/Q9E2G5_9VIRU Q9E2G5_9VIRU] | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | Penaeus stylirostris densovirus (PstDNV), a pathogen of penaeid shrimp, causes significant damage to farmed and wild shrimp populations. In contrast to other parvoviruses, PstDNV probably has only one type of capsid protein that lacks the phospholipase A2 activity that has been implicated as a requirement during parvoviral host cell infection. The structure of recombinant virus-like particles, composed of 60 copies of the 37.5-kDa coat protein, the smallest parvoviral capsid protein reported thus far, was determined to 2.5-A resolution by X-ray crystallography. The structure represents the first near-atomic resolution structure within the genus Brevidensovirus. The capsid protein has a beta-barrel "jelly roll" motif similar to that found in many icosahedral viruses, including other parvoviruses. The N-terminal portion of the PstDNV coat protein adopts a "domain-swapped" conformation relative to its twofold-related neighbor similar to the insect parvovirus Galleria mellonella densovirus (GmDNV) but in stark contrast to vertebrate parvoviruses. However, most of the surface loops have little structural resemblance to any of the known parvoviral capsid proteins. | ||
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| - | Structure of Penaeus stylirostris densovirus, a shrimp pathogen.,Kaufmann B, Bowman VD, Li Y, Szelei J, Waddell PJ, Tijssen P, Rossmann MG J Virol. 2010 Nov;84(21):11289-96. Epub 2010 Aug 11. PMID:20702621<ref>PMID:20702621</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 3n7x" style="background-color:#fffaf0;"></div> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
Crystal structure of Penaeus stylirostris densovirus capsid
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