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6o2c
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==Crystal structure of 4493 Fab in complex with circumsporozoite protein NANP3 and anti-kappa VHH domain== |
| - | <StructureSection load='6o2c' size='340' side='right'caption='[[6o2c]]' scene=''> | + | <StructureSection load='6o2c' size='340' side='right'caption='[[6o2c]], [[Resolution|resolution]] 2.02Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6o2c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O2C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6O2C FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6o2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o2c OCA], [https://pdbe.org/6o2c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6o2c RCSB], [https://www.ebi.ac.uk/pdbsum/6o2c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6o2c ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.017Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6o2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o2c OCA], [https://pdbe.org/6o2c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6o2c RCSB], [https://www.ebi.ac.uk/pdbsum/6o2c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6o2c ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CSP_PLAFO CSP_PLAFO] The circumsporozoite protein is the immunodominant surface antigen on the sporozoite (the infective stage of the malaria parasite that is transmitted from the mosquito to the vertebrate host). | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Lama glama]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Plasmodium falciparum]] |
| + | [[Category: Bosch A]] | ||
| + | [[Category: Julien JP]] | ||
| + | [[Category: Murugan R]] | ||
| + | [[Category: Prieto K]] | ||
| + | [[Category: Scally SW]] | ||
| + | [[Category: Wardemann H]] | ||
Current revision
Crystal structure of 4493 Fab in complex with circumsporozoite protein NANP3 and anti-kappa VHH domain
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