7x4o

<StructureSection load='7x4o' size='340' side='right'caption='[[7x4o]], [[Resolution|resolution]] 2.02&Aring;' scene=''>

<table><tr><td colspan='2'>[[7x4o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X4O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X4O FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.02&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x4o OCA], [https://pdbe.org/7x4o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x4o RCSB], [https://www.ebi.ac.uk/pdbsum/7x4o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x4o ProSAT]</span></td></tr>

== Function ==

[https://www.uniprot.org/uniprot/VPS17_YEAST VPS17_YEAST] Plays a role in vesicular protein sorting. Required for the sorting and delivery of a subset of soluble vacuolar hydrolases. Required for retention of late Golgi membrane proteins and vacuolar biogenesis. Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport. The VPS5-VPS17 subcomplex may assemble onto the membrane to promote vesicle formation.

==See Also==

*[[Vacuolar protein sorting-associated protein 3D structures|Vacuolar protein sorting-associated protein 3D structures]]

[[Category: Saccharomyces cerevisiae S288C]]