1rii

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[[Image:1rii.gif|left|200px]]
[[Image:1rii.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1rii |SIZE=350|CAPTION= <scene name='initialview01'>1rii</scene>, resolution 1.70&Aring;
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The line below this paragraph, containing "STRUCTURE_1rii", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoglycerate_mutase Phosphoglycerate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.2.1 5.4.2.1] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= GPMA, GPM, PGM, GPM1, RV0489, MT0508, MTCY20G9.15, MB0499 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
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-->
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0588 GpmA]</span>
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{{STRUCTURE_1rii| PDB=1rii | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rii OCA], [http://www.ebi.ac.uk/pdbsum/1rii PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1rii RCSB]</span>
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}}
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'''Crystal structure of phosphoglycerate mutase from M. Tuberculosis'''
'''Crystal structure of phosphoglycerate mutase from M. Tuberculosis'''
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[[Category: TBSGC, TB Structural Genomics Consortium.]]
[[Category: TBSGC, TB Structural Genomics Consortium.]]
[[Category: Wu, Y.]]
[[Category: Wu, Y.]]
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[[Category: phosphoglyerate mutase]]
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[[Category: Phosphoglyerate mutase]]
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[[Category: protein structure initiative]]
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[[Category: Protein structure initiative]]
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[[Category: psi]]
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[[Category: Psi]]
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[[Category: sh3 domain binding]]
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[[Category: Sh3 domain binding]]
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[[Category: structural genomic]]
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[[Category: Structural genomic]]
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[[Category: tb structural genomics consortium]]
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[[Category: Tb structural genomics consortium]]
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[[Category: tbsgc]]
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[[Category: Tbsgc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 07:32:14 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:28:39 2008''
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Revision as of 04:32, 3 May 2008

Image:1rii.gif

Template:STRUCTURE 1rii

Crystal structure of phosphoglycerate mutase from M. Tuberculosis


Overview

The single-crystal X-ray structure of phosphoglycerate mutase from Mycobacterium tuberculosis has been determined at a resolution of 1.70 angstroms. The C-terminal tail of each of the subunits is flexible and disordered; however, for one of the four chains (chain A) all but five residues of the chain could be modeled. Noteworthy features of the structure include the active site and a proline-rich segment in each monomer forming a short left-handed polyprolyl helix. These segments lie on the enzyme surface and could conceivably participate in protein-protein interactions.

About this Structure

1RII is a Single protein structure of sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

The 1.70 angstroms X-ray crystal structure of Mycobacterium tuberculosis phosphoglycerate mutase., Muller P, Sawaya MR, Pashkov I, Chan S, Nguyen C, Wu Y, Perry LJ, Eisenberg D, Acta Crystallogr D Biol Crystallogr. 2005 Mar;61(Pt 3):309-15. Epub 2005, Feb 24. PMID:15735341 Page seeded by OCA on Sat May 3 07:32:14 2008

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