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User:Merritt Jugo/Sandbox 1

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==Introduction==
==Introduction==
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The RNA lariat debranching enzyme, Dbr1, is a metallophosphoesterase that cleaves 2'-5' phosphodiester bonds within intronic lariats. <ref name="Ransey">PMID:28504306</ref>
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Peter piper picked a pack of pickled peppers.
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Previous reports have indicated that Dbr1 enzymatic activity is supported by diverse metal ions including Ni2+ , Mn2+ , Mg2+ , Fe2+ , and Zn2+ . <ref name="Ransey"/>
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sally sells seashells by the sea shore.
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ICP-AES corroborate this finding, and in vitro debranching assays with fluorescently labeled branched substrates confirm activity. <ref name="Ransey"/>
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Revision as of 18:53, 9 April 2024

Merritt's Take on DPPIV

Dipeptidyl Peptidase IV (6B1E)

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References

[3]

  1. Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
  3. Deacon CF. Physiology and Pharmacology of DPP-4 in Glucose Homeostasis and the Treatment of Type 2 Diabetes. Front Endocrinol (Lausanne). 2019 Feb 15;10:80. PMID:30828317 doi:10.3389/fendo.2019.00080

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