8io3

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Current revision (07:58, 10 April 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8io3 is ON HOLD until 2025-04-10
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==Cryo-EM structure of human HCN3 channel with cilobradine==
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<StructureSection load='8io3' size='340' side='right'caption='[[8io3]], [[Resolution|resolution]] 3.02&Aring;' scene=''>
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Authors: Yu, B., Lu, Q.Y., Li, J., Zhang, J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8io3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IO3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IO3 FirstGlance]. <br>
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Description: Cryo-EM structure of human HCN3 channel with cilobradine
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.02&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VXI:3-[[(3~{S})-1-[2-(3,4-dimethoxyphenyl)ethyl]piperidin-3-yl]methyl]-7,8-dimethoxy-2,5-dihydro-1~{H}-3-benzazepin-4-one'>VXI</scene></td></tr>
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[[Category: Li, J]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8io3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8io3 OCA], [https://pdbe.org/8io3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8io3 RCSB], [https://www.ebi.ac.uk/pdbsum/8io3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8io3 ProSAT]</span></td></tr>
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[[Category: Zhang, J]]
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</table>
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[[Category: Lu, Q.Y]]
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== Function ==
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[[Category: Yu, B]]
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[https://www.uniprot.org/uniprot/HCN3_HUMAN HCN3_HUMAN] Hyperpolarization-activated potassium channel. May also facilitate the permeation of sodium ions.<ref>PMID:16043489</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Li J]]
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[[Category: Lu QY]]
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[[Category: Yu B]]
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[[Category: Zhang J]]

Current revision

Cryo-EM structure of human HCN3 channel with cilobradine

PDB ID 8io3

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