1rlb

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[[Image:1rlb.gif|left|200px]]
[[Image:1rlb.gif|left|200px]]
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{{Structure
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The line below this paragraph, containing "STRUCTURE_1rlb", creates the "Structure Box" on the page.
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|LIGAND= <scene name='pdbligand=REA:RETINOIC+ACID'>REA</scene>
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{{STRUCTURE_1rlb| PDB=1rlb | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rlb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rlb OCA], [http://www.ebi.ac.uk/pdbsum/1rlb PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1rlb RCSB]</span>
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'''RETINOL BINDING PROTEIN COMPLEXED WITH TRANSTHYRETIN'''
'''RETINOL BINDING PROTEIN COMPLEXED WITH TRANSTHYRETIN'''
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[[Category: Monaco, H L.]]
[[Category: Monaco, H L.]]
[[Category: Rizzi, M.]]
[[Category: Rizzi, M.]]
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[[Category: complex (protein/protein)]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 07:38:17 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:29:44 2008''
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Revision as of 04:38, 3 May 2008

Image:1rlb.gif

Template:STRUCTURE 1rlb

RETINOL BINDING PROTEIN COMPLEXED WITH TRANSTHYRETIN


Overview

The three-dimensional structure of the complex formed by two plasma proteins, transthyretin and retinol-binding protein, was determined from x-ray diffraction data to a nominal resolution of 3.1 angstroms. One tetramer of transthyretin was bound to two molecules of retinol-binding protein. The two retinol-binding protein molecules established molecular interactions with the same transthyretin dimer, and each also made contacts with one of the other two monomers. Thus, the other two potential binding sites in a transthyretin tetramer were blocked. The amino acid residues of the retinol-binding protein that were involved in the contacts were close to the retinol-binding site.

About this Structure

1RLB is a Protein complex structure of sequences from Gallus gallus and Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structure of a complex of two plasma proteins: transthyretin and retinol-binding protein., Monaco HL, Rizzi M, Coda A, Science. 1995 May 19;268(5213):1039-41. PMID:7754382 Page seeded by OCA on Sat May 3 07:38:17 2008

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