1ne3
From Proteopedia
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==Solution structure of ribosomal protein S28E from Methanobacterium Thermoautotrophicum. Ontario Centre for Structural Proteomics target MTH0256_1_68; Northeast Structural Genomics Target TT744== | ==Solution structure of ribosomal protein S28E from Methanobacterium Thermoautotrophicum. Ontario Centre for Structural Proteomics target MTH0256_1_68; Northeast Structural Genomics Target TT744== | ||
- | <StructureSection load='1ne3' size='340' side='right'caption='[[1ne3 | + | <StructureSection load='1ne3' size='340' side='right'caption='[[1ne3]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[1ne3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1ne3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermococcus_thermolithotrophicus Methanothermococcus thermolithotrophicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NE3 FirstGlance]. <br> |
- | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ne3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ne3 OCA], [https://pdbe.org/1ne3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ne3 RCSB], [https://www.ebi.ac.uk/pdbsum/1ne3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ne3 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ne3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ne3 OCA], [https://pdbe.org/1ne3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ne3 RCSB], [https://www.ebi.ac.uk/pdbsum/1ne3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ne3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/RS28_METTH RS28_METTH] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ne3 ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ne3 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
- | <div style="background-color:#fffaf0;"> | ||
- | == Publication Abstract from PubMed == | ||
- | The ribosomal protein S28E from the archaeon Methanobacterium thermoautotrophicum is a component of the 30S ribosomal subunit. Sequence homologs of S28E are found only in archaea and eukaryotes. Here we report the three-dimensional solution structure of S28E by NMR spectroscopy. S28E contains a globular region and a long C-terminal tail protruding from the core. The globular region consists of four antiparallel beta-strands that are arranged in a Greek-key topology. Unique features of S28E include an extended loop L2-3 that folds back onto the protein and a 12-residue charged C-terminal tail with no regular secondary structure and greater flexibility relative to the rest of the protein. The structural and surface resemblance to OB-fold family of proteins and the presence of highly conserved basic residues suggest that S28E may bind to RNA. A broad positively charged surface extending over one side of the beta-barrel and into the flexible C terminus may present a putative binding site for RNA. | ||
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- | Solution structure of ribosomal protein S28E from Methanobacterium thermoautotrophicum.,Wu B, Yee A, Pineda-Lucena A, Semesi A, Ramelot TA, Cort JR, Jung JW, Edwards A, Lee W, Kennedy M, Arrowsmith CH Protein Sci. 2003 Dec;12(12):2831-7. PMID:14627743<ref>PMID:14627743</ref> | ||
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- | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
- | </div> | ||
- | <div class="pdbe-citations 1ne3" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
*[[Ribosomal protein S28|Ribosomal protein S28]] | *[[Ribosomal protein S28|Ribosomal protein S28]] | ||
- | == References == | ||
- | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: Atcc 35097]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: | + | [[Category: Methanothermococcus thermolithotrophicus]] |
- | [[Category: | + | [[Category: Arrowsmith CH]] |
- | [[Category: | + | [[Category: Cort JR]] |
- | [[Category: | + | [[Category: Edwards A]] |
- | [[Category: | + | [[Category: Kennedy M]] |
- | [[Category: Pineda-Lucena | + | [[Category: Pineda-Lucena A]] |
- | [[Category: Ramelot | + | [[Category: Ramelot TA]] |
- | [[Category: Wu | + | [[Category: Wu B]] |
- | [[Category: Yee | + | [[Category: Yee A]] |
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Revision as of 08:48, 10 April 2024
Solution structure of ribosomal protein S28E from Methanobacterium Thermoautotrophicum. Ontario Centre for Structural Proteomics target MTH0256_1_68; Northeast Structural Genomics Target TT744
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