1nu0
From Proteopedia
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<StructureSection load='1nu0' size='340' side='right'caption='[[1nu0]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='1nu0' size='340' side='right'caption='[[1nu0]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1nu0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1nu0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NU0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NU0 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nu0 OCA], [https://pdbe.org/1nu0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nu0 RCSB], [https://www.ebi.ac.uk/pdbsum/1nu0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nu0 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nu0 OCA], [https://pdbe.org/1nu0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nu0 RCSB], [https://www.ebi.ac.uk/pdbsum/1nu0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nu0 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/YQGF_ECOLI YQGF_ECOLI] Involved in the processing of the 5'-end of pre-16S rRNA during 70S ribosome maturation (processing does not occur on total cellular RNA off the ribosome); may be a nuclease (PubMed:25545592). A temperature-sensitive yqgF mutant no longer grows when Rho or NusA are overproduced, and has reduced transcription of genes encoded downstream of Rho terminators; transcription increases again in the presence of the Rho inhibitor bicylomycin (PubMed:22353788).<ref>PMID:22353788</ref> <ref>PMID:25545592</ref> | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia coli]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Galkin | + | [[Category: Galkin A]] |
| - | [[Category: Herzberg | + | [[Category: Herzberg O]] |
| - | [[Category: Howard | + | [[Category: Howard A]] |
| - | [[Category: Krajewski | + | [[Category: Krajewski W]] |
| - | + | [[Category: Sarikaya E]] | |
| - | [[Category: Sarikaya | + | |
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Revision as of 08:53, 10 April 2024
Structure of the double mutant (L6M; F134M, SeMet form) of yqgF from Escherichia coli, a hypothetical protein
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