8gyo

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m (Protected "8gyo" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 8gyo is ON HOLD
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==Inner channel lipids regulated gating mechanism of human pannexins.==
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<StructureSection load='8gyo' size='340' side='right'caption='[[8gyo]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8gyo]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GYO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GYO FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AJP:Digitonin'>AJP</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gyo OCA], [https://pdbe.org/8gyo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gyo RCSB], [https://www.ebi.ac.uk/pdbsum/8gyo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gyo ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PANX1_HUMAN PANX1_HUMAN] Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis.<ref>PMID:16908669</ref> <ref>PMID:20829356</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Cong Y]]
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[[Category: Jin X]]
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[[Category: Kong F]]
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[[Category: Yan C]]

Revision as of 05:25, 17 April 2024

Inner channel lipids regulated gating mechanism of human pannexins.

PDB ID 8gyo

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OCA

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