8rhr

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Current revision (05:28, 17 April 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8rhr is ON HOLD until Paper Publication
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==E.coli Peptide Deformylase with bound inhibitor BB4==
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<StructureSection load='8rhr' size='340' side='right'caption='[[8rhr]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
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Authors: Kirschner, H., Stoll, R., Hofmann, E.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8rhr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RHR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RHR FirstGlance]. <br>
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Description: E.coli Peptide Deformylase with bound inhibitor BB4
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.42&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB4:2-(5-BROMO-1H-INDOL-3-YL)-N-HYDROXYACETAMIDE'>BB4</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Kirschner, H]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rhr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rhr OCA], [https://pdbe.org/8rhr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rhr RCSB], [https://www.ebi.ac.uk/pdbsum/8rhr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rhr ProSAT]</span></td></tr>
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[[Category: Stoll, R]]
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</table>
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[[Category: Hofmann, E]]
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== Function ==
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[https://www.uniprot.org/uniprot/C3SRA2_ECOLX C3SRA2_ECOLX] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Large Structures]]
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[[Category: Hofmann E]]
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[[Category: Kirschner H]]
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[[Category: Stoll R]]

Current revision

E.coli Peptide Deformylase with bound inhibitor BB4

PDB ID 8rhr

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